Vinyl halides
Medchemexpress LLC Trans-2-butene-1,4-dicarboxylic acid | 4436-74-2 | 99.2% | 1 ML
Trans-2-butene-1,4-dicarboxylic acid is an endogenous metabolite appearing as a white to off-white solid. This product is strictly for research use.
- Endogenous metabolite
- For research use only
- Metabolite for organic acidurias found in urine
Medchemexpress LLC Carbazochrome (sodium sulfonate) | 51460-26-5 | 98.0% | 100 MG
Carbazochrome sodium sulfonate (AC-17) is a capillary stabilizer and an antihemorrhagic agent for hemorrhage research.
- Inhibits Bradykinin-induced and thrombin-induced formation of [3H]IP3
- Suppresses permeability enhancement induced by vasoactive substances
- Attenuates pulmonary dysfunction induced by radiographic contrast media
- For research use only
Medchemexpress LLC Benzo[c]-2,6-naphthyridine-8-carboxylic acid, 5-[(3-chlorophenyl)amino]-, sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 1 ML
Silmitasertib sodium salt is an orally bioavailable, highly selective, and potent CK2 inhibitor with IC50 values of 1 nM against CK2α and CK2α'. It exhibits potent anti-cancer activity.
- Orally bioavailable and potent CK2 inhibitor
- Highly selective for CK2α and CK2α'
- Causes cell-cycle arrest and induces apoptosis in cancer cells
- Attenuates PI3K/Akt signaling
- Demonstrates robust antitumor activity in murine xenograft models
- Suitable for research use only
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.92% | C19H11ClN3NaO2 | 1 G
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'. It induces cell-cycle arrest and selectively induces apoptosis in cancer cells, attenuates PI3K/Akt signaling, and its antiproliferative activity correlates with CK2α catalytic subunit expression. It also prevents leukemic cells from engaging a functional UPR and decreases pro-survival ER chaperon BIP/Grp78 expression.
- Highly selective and potent CK2 inhibitor (IC50 of 1 nM against CK2α and CK2α')
- Induces cell-cycle arrest and selective apoptosis in cancer cells
- Attenuates PI3K/Akt signaling and suppresses CK2-mediated PI3K/Akt/mTOR signaling
- Exerts anti-proliferative effects in hematological tumors
- Prevents leukemic cells from engaging a functional UPR and decreases pro-survival ER chaperon BIP/Grp78 expression
Medchemexpress LLC Prexigebersen sodium | C177H206N63Na18O110P17 | 5 MG
Prexigebersen sodium is an antisense oligonucleotide engineered to obstruct the protein synthesis of Grb2 (growth factor receptor bound protein 2). It is intended for research purposes only and not for patient use. The product is an off-white to light yellow solid with a molecular weight of 5520.6 (free acid).
- Antisense oligonucleotide designed to inhibit Grb2 protein synthesis
- Appearance: off-white to light yellow solid
- Purity: 98.95%
- Solubility: soluble in H2O at concentrations ≥ 100 mg/mL
- Shipping: shipped at room temperature within the continental US
- Storage: store solid form at -20°C, sealed, and away from moisture; in solvent store at -80°C for up to 6 months, or -20°C for 1 month, sealed and away from moisture
Medchemexpress LLC Alizarin Red S sodium | 130-22-3 | 25 MG
Alizarin Red S sodium is an anthraquinone-derived dye that binds calcium ions and is used to stain mineralized deposits in biological samples. It is commonly used in histology and cell biology to assess osteoblast differentiation and bone formation.
- Stains calcium deposits for histology and cell-based assays.
- Forms complexes with calcium for visualization of mineralized matrix.
- Water-soluble sodium salt suitable for aqueous staining procedures.
- Supplied in small laboratory quantities for research use.
Medchemexpress LLC Prexigebersen sodium | C177H206N63Na18O110P17 | 1 MG
Prexigebersen sodium is an antisense oligonucleotide designed to inhibit protein synthesis of Grb2 (growth factor receptor bound protein 2). It is for research use only.
- Purity: 98.95%
- Chemical structure: DNA, d(P-ethyl)(A-T-A-T-T-T-G-G-C-G-A-T-G-G-C-T-T-C), sodium salt
- Molecular weight: 5520.6 (free acid)
- Appearance: Solid
- Color: Off-white to light yellow
- Target: ERK
- Pathway: MAPK/ERK pathway; Stem cell/Wnt
- Solubility (in vitro): H2O: ≥ 100 mg/mL
- Storage: -20°C, sealed, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
Medchemexpress LLC Flucloxacillin sodium | 1847-24-1 | 98.0% | C19H16ClFN3NaO5S | 1 ML
Flucloxacillin sodium is an active antibiotic effective against gram-positive and gram-negative bacteria. It is for research use only and not sold to patients. In a study with male Wistar rats, Flucloxacillin sodium (200 mg/kg; i.p.; three times/day, for 21 days) was effective against common bacterial strains in periprosthetic infection, leading to reduced germs in the biofilm and bone tissue.
- Active against gram-positive and gram-negative bacteria.
- Effective in reducing germs in biofilm and bone tissue in a rat study.
- For research use only.
Medchemexpress LLC Flucloxacillin sodium | 1847-24-1 | 98.0% | C19H16ClFN3NaO5S | 1 G
Flucloxacillin sodium is an active antibiotic that effectively targets both gram-positive and gram-negative bacteria. With a purity of 98.02%, it is commonly used in research and has shown efficacy in reducing germs in biofilm and bone tissue in periprosthetic infections. This compound is also being investigated in various clinical trials for conditions such as cellulitis, wound infection, and osteomyelitis.
- Active against gram-positive and gram-negative bacteria
- Effective in periprosthetic infection models
- Reduces germs in biofilm and bone tissue
- Purity of 98.02%
- Soluble in water and DMSO
- Involved in clinical trials for various bacterial infections
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 100 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor.
- Causes cell-cycle arrest and selectively induces apoptosis in cancer cells by attenuating PI3K/Akt signaling.
- Antiproliferative activity correlates with CK2α catalytic subunit expression.
- Prevents leukemic cells from engaging UPR during PS-341 treatment, reducing BIP/Grp78 expression.
- Induces cytotoxicity and apoptosis, exerting anti-proliferative effects in hematological tumors.
- Demonstrates robust antitumor activity and reduces phospho-p21 (T145) in murine xenograft models.
Medchemexpress LLC Cyclamic acid (sodium) | 139-05-9 | MFCD00003827 | 99.9% | 201.22 g/mol | C6H12NNaO3S | 1 ML
Cyclamic acid (sodium) is the sodium salt of cyclohexylsulfamic acid supplied for research and analytical applications in solid and pre-made solution formats. It is used as an artificial sweetener reference and an analytical standard for chromatographic and mass spectrometry methods.
- High purity: 99.94% (analytical standard)
- Available as 10 mM x 1 mL solution in DMSO for convenience
- Suitable for HPLC, GC, and mass spectrometry workflows
- Solubility guidance provided for water and DMSO to aid assay preparation
- Storage recommendations: solid at 4°C; in solvent at -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC N-Caproicacid sodiu 25g
N-caproicacid sodium is an anionic surfactant sodium n-caproic acid
Medchemexpress LLC Ponceau 4R (Acid Red 18; New Coccine) | 2611-82-7 | 85.0% | 5 G
Ponceau 4R (85%) is a synthetic strawberry red azo dye used as a food coloring. It is synthesized from aromatic hydrocarbons and is stable to light, heat, and acid, but fades in the presence of ascorbic acid. It is intended for research use only.
- Synthetic colorant that may be used as a food coloring.
- Strawberry red azo dye.
- Stable to light, heat, and acid (fades in the presence of ascorbic acid).